genomic testing

23 posts

What are some of the hematologic manifestations of VEXAS syndrome?

What are some of the hematologic manifestations of VEXAS syndrome?

A Man with a Recurrent Left Pleural Effusion In late 2020, a new disease entity that was referred to as VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome was reported. Q: What is the cause of VEXAS syndrome?A: VEXAS syndrome is caused by somatic mutations in UBA1 (the gene that encodes ubiquitin-like modifier activating enzyme 1), which initiates […]

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Determining clinical course of diffuse large B-cell lymphoma using targeted transcriptome and machine learning algorithms

Abstract Multiple studies have demonstrated that diffuse large B-cell lymphoma (DLBCL) can be divided into subgroups based on their biology; however, these biological subgroups overlap clinically. Using machine learning, we developed an approach to stratify patients with DLBCL into four subgroups based on survival characteristics. This approach uses data from the targeted transcriptome to predict […]

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Genomic Testing Cooperative Announces Collaboration with Elevation Oncology to Expand Comprehensive Genomic Testing for NRG1 Fusions Across Solid Tumors in Support of the Phase 2 CRESTONE Study

Irvine, CA – June 30th – Genomic Testing Cooperative, a first-in-class diagnostic company based on a cooperative business model (Co-Op) using the most recent advances in NGS technology, announced today a collaboration with Elevation Oncology to enhance identification of patients with any solid tumor harboring an NRG1 fusion who may be eligible for enrollment in […]

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GTC scientists contribute to major study published in Journal of Clinical Oncology: Prediction of outcome in CLL patients

GTC scientists contribute to major study published in Journal of Clinical Oncology: Prediction of outcome in CLL patients

GTC scientists collaborate with the NIH on a study just published in the Journal of Clinical Oncology. The publication is titled: Prediction of outcome in CLL patients treated with ibrutinib: development and validation of a four-factor prognostic model. You can read the article here (subscription required). Abstract: PURPOSE Randomized trials established the superiority of ibrutinib-based […]

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Utilize the first AI software for diagnosing DLBCL

Utilize the first AI software for diagnosing DLBCL

GTC is the first and only diagnostic lab to deploy true artificial intelligence (AI) software for classifications of lymphoma. Do not accept partial results, send your lymphoma to GTC for comprehensive classification using RNA/DNA and artificial intelligence. Get results in 7 days for DNA and 10 days for RNA GTC was recently published in Blood […]

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Hackensack Meridian Health Partners with GTC to Establish a Reference Laboratory Offering State-of-the-Art Genomic Precision Testing

Hackensack Meridian Health Partners with Genomic Testing Cooperative to Establish a Reference Laboratory Offering State-of-the-Art Genomic Precision Testing

IRVINE, Calif. and EDISON, N.J., July 22, 2020 /PRNewswire/ — Hackensack Meridian Health (HMH) in Edison, New Jersey, and Genomic Testing Cooperative (GTC), Irvine, California, announced today an agreement to establish a next generation sequencing reference laboratory for molecular profiling. The state-of-the-art laboratory, located at JFK Medical Center in Edison, New Jersey, will use artificial intelligence […]

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GTC research is being presented at ASCO 2020

GTC research is being presented at ASCO 2020

GTC research is being presented at ASCO 2020 in the following three abstracts. 1. FGFR expression, fusion and mutation as detected by NGS sequencing of DNA and RNA. * 2. Measuring PD-L1 mRNA expression using targeted next generation sequencing and correlation with interferon pathway activation genes in lung and colorectal cancers. * 3. Bimodal ntrk […]

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New Collaboration to Offer Liquid Biopsy Testing

Genomic Testing Cooperative New Collaboration to Offer Liquid Biopsy Testing

Genomic Testing Cooperative (GTC) and C2i Genomics Announce Collaboration to Offer Liquid Biopsy Testing for Staging and Monitoring Solid Tumors Based on Pattern Recognition of Whole Genome DNA Signature IRVINE, Calif. and NEW YORK, Jan. 14, 2020 /PRNewswire/ — Genomic Testing Cooperative, LCA (GTC), a cooperative (Co-Op) company offering comprehensive genomic profiling of hematologic and […]

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