A Man with a Recurrent Left Pleural Effusion In late 2020, a new disease entity that was referred to as VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome was reported. Q: What is the cause of VEXAS syndrome?A: VEXAS syndrome is caused by somatic mutations in UBA1 (the gene that encodes ubiquitin-like modifier activating enzyme 1), which initiates […]
Abstract Multiple studies have demonstrated that diffuse large B-cell lymphoma (DLBCL) can be divided into subgroups based on their biology; however, these biological subgroups overlap clinically. Using machine learning, we developed an approach to stratify patients with DLBCL into four subgroups based on survival characteristics. This approach uses data from the targeted transcriptome to predict […]
Irvine, CA – June 30th – Genomic Testing Cooperative, a first-in-class diagnostic company based on a cooperative business model (Co-Op) using the most recent advances in NGS technology, announced today a collaboration with Elevation Oncology to enhance identification of patients with any solid tumor harboring an NRG1 fusion who may be eligible for enrollment in […]
GTC scientists collaborate with the NIH on a study just published in the Journal of Clinical Oncology. The publication is titled: Prediction of outcome in CLL patients treated with ibrutinib: development and validation of a four-factor prognostic model. You can read the article here (subscription required). Abstract: PURPOSE Randomized trials established the superiority of ibrutinib-based […]
Jul 23, 2020 | John Gilmore NEW YORK – As part of plans to establish a country-wide network of labs for minimizing the cost of sequencing, Genomic Testing Cooperative (GTC) has launched a joint venture with Hackensack Meridian Health (HMH) that will analyze clinical samples from patients with a variety of different cancers. The Irvine, […]
GTC is the first and only diagnostic lab to deploy true artificial intelligence (AI) software for classifications of lymphoma. Do not accept partial results, send your lymphoma to GTC for comprehensive classification using RNA/DNA and artificial intelligence. Get results in 7 days for DNA and 10 days for RNA GTC was recently published in Blood […]
IRVINE, Calif. and EDISON, N.J., July 22, 2020 /PRNewswire/ — Hackensack Meridian Health (HMH) in Edison, New Jersey, and Genomic Testing Cooperative (GTC), Irvine, California, announced today an agreement to establish a next generation sequencing reference laboratory for molecular profiling. The state-of-the-art laboratory, located at JFK Medical Center in Edison, New Jersey, will use artificial intelligence […]
GTC research is being presented at ASCO 2020 in the following three abstracts. 1. FGFR expression, fusion and mutation as detected by NGS sequencing of DNA and RNA. * 2. Measuring PD-L1 mRNA expression using targeted next generation sequencing and correlation with interferon pathway activation genes in lung and colorectal cancers. * 3. Bimodal ntrk […]
GTC featured in the Orange County Business Journal on February 3, 2020
Genomic Testing Cooperative (GTC) and C2i Genomics Announce Collaboration to Offer Liquid Biopsy Testing for Staging and Monitoring Solid Tumors Based on Pattern Recognition of Whole Genome DNA Signature IRVINE, Calif. and NEW YORK, Jan. 14, 2020 /PRNewswire/ — Genomic Testing Cooperative, LCA (GTC), a cooperative (Co-Op) company offering comprehensive genomic profiling of hematologic and […]