Monthly Archives: February 2019

Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia

Order GTC Hematology Expression/Fusion Profile   The GTC Hematology Expression/Fusion test provides actionable information for: 1) Determining Fusion and classification (Ph-Positive or Ph-Like) Acute lymphoblastic leukemia (ALL) is a heterogeneous disease with genomic alterations dominated by structural chromosomal abnormalities, particularly translocations. Most of the reported chromosomal translocations in ALL lead to the expression of fusion RNAs and proteins that frequently upregulate expression of oncoproteins or the expression of more potent oncoprotein. Philadelphia chromosome-positive (Ph1) ALL is one of the subtypes of ALL that is characterized by t(9;22)(q34;q11) and produces constitutively active BCR-ABL1 fusion oncoprotein. Ph-positive ALL is common in adults and detected in almost 25% of patients but rare in […]

23rd Annual International Congress on Hematologic Malignancies 2019

23rd Annual International Congress on Hematologic Malignancies 2019

23rd Annual International Congress on Hematologic Malignancies 2019: Focus on Leukemias, Lymphomas and Myeloma   The annual International Congress on Hematologic Malignancies is dedicated to providing clinicians access to emerging data in treating hematologic malignancies. Providing practical tools to optimize therapy and personalize care. Our Chief Medical Officer Dr. Maher Albitar will be presenting Beyond Genomics: Integrating Molecular Medicine in Our Practice on Friday March 1st, 8:40am. Few words about the Congress Now in its 23rd year, the annual International Congress on Hematologic Malignancies®: Focus on Leukemias, Lymphomas, and Myeloma provides practitioners who manage hematologic malignancies the practical tools to translate emerging data into the best therapy for patients with these tumors, […]

Diffuse Large B-Cell Lymphoma (DLBCL)

Diffuse Large B-Cell Lymphoma (DLBCL)

Order GTC Hematology Expression/Fusion Profile GTC Hematology Expression/Fusion Profiling provides highly informative and actionable data for patients with DLBCL as follows: 1) B-cell Markers: This assay provides data on the expression of markers specific to B-cell. It will report the levels of expression of B-cell markers, including CD19, CD79A, CD79B, PAX5, CD22, and others. The levels of CD274 (PD-L1) will also be determined and reported. After confirming that the case is B-cell neoplasm, multiple algorithms and deep learning are used to determine the following: 2) Cell of Origin (COO): Diffuse large B-cell lymphomas (DLBCLs) are clinically heterogeneous group and outcome varies significantly between patients irrespective of treatment protocol. However, determining […]

Sarcoma Diagnosis and Classification

Sarcoma Diagnosis and Classification

Order GTC Solid Tumor Expression/Fusion Profile Sarcoma Diagnosis and Classification. The GTC Solid Tumor Expression/Fusion Profiling provides highly informative and actionable data for patients with sarcoma. Sarcomas are heterogeneous group of cancer that arises in the connective tissue. Diagnosis and subclassification of sarcoma can be very difficult due to overlapping in histological and immunohistological features. Determining the molecular abnormalities, especially fusion genes and chromosomal translocations in a specific sarcoma can be very helpful in diagnosis, subclassification and determining therapy. Sarcoma is a rare cancer type, but it is relatively more common in pediatric patients. In general, the presence of a specific translocation in one sarcoma type does not occur in […]

Before you go...Let's stay in touch!
Subscribe on our list

- Get the Latest News
- Get Notified on upcoming events

* Your email is safe with us. We hate spamming, as much as you do!